Nonsteroidal anti-inflammatory drugs may negate the usefulness of feverfew in the treatment of migraine headaches.

Pregnant women should not use the herb, it may stimulate uterine contractions.

Fresh leaves may cause mouth ulcers, abdominal pain, or experience loss of taste. If these symptoms develop, discontinue use and notify your doctor.

Feverfew may interfere with the blood's clotting ability; talk to your doctor before using if you have a clotting disorder or take anticoagulant medicine.

You may need to take feverfew daily for two to three months before it has any effect.

Feverfew may increase the risk of bleeding or potentiate the effects of warfarin therapy.

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