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Do not use if you are pregnant or nursing. Ginkgo can cause headaches, seizures, irritability, restlessness, diarrhea, nausea, and vomiting; if these symptoms develop, check with your practitioner to see if you should lower your dosage or stop taking ginkgo completely. Some people are unable to tolerate ginkgo even in small doses. Do not use if you have a clotting disorder. Do not give ginkgo to children without a doctor's supervision. Use in medicinal amounts only in consultation with a healthcare professional. Ingestion of the fruit pulp can cause severe gastrointestinal irritation, erythema and edema, and the rapid formation of vesicles resulting in severe itching. Ginkgo reinforces warfarin action by heterogeneous mechanisms. It should thus not be used in patients on oral anticoagulant and/or antiplatelet therapy. - Oral anticoagulants and medicinal plants. An emerging interaction -- Argento A, Tiraferri E, Marzaloni M. -- Ann Ital Med Int. 2000 Apr;15(2):139-43. Ginkgo may increase the risk of bleeding or potentiate the effects of warfarin therapy. - Am J Health Syst Pharm 2000 Jul 1;57(13):1221-7; quiz 1228-30 -- Potential interactions between alternative therapies and warfarin. -- Heck AM, DeWitt BA, Lukes AL. Interactions include bleeding when combined with warfarin, raised blood pressure when combined with a thiazide diuretic and coma when combined with trazodone. - Drugs 2001;61(15):2163-75 -- Interactions between herbal medicines and prescribed drugs: a systematic review. -- Izzo AA, Ernst E. The standardized extract of Ginkgo biloba has an inhibitory action on blood pressure and it may influence cortisol release in response to some stress stimuli. - J Physiol Pharmacol 2002 Sep;53(3):337-48 -- Reduction of rise in blood pressure and cortisol release during stress by Ginkgo biloba extract (EGb 761) in healthy volunteers. -- Jezova D, Duncko R, Lassanova M, Kriska M, Moncek F. Ginkgo and trazodone may cause an adverse interaction. - Drugs Aging 2002;19(11):879-86 -- Potential Interactions between Herbal Medicines and Conventional Drug Therapies Used by Older Adults Attending a Memory Clinic. -- Dergal JM, Gold JL, Laxer DA, Lee MS, Binns MA, Lanctot KL, Freedman M, Rochon PA.
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