Goldenseal is a potent plant and must be used with care.
Do not take on a daily basis for more than a week at a time.
Eating the fresh plant can cause inflammation of the mucous tissue
In high doses, goldenseal can irritate the skin, mouth, throat, and vagina. If
any of these develop, stop taking immediately.
It may cause nausea and diarrhea. If any of these develop, stop taking
Do not use during pregnancy; it may stimulate the uterus.
Do not use goldenseal without consulting a physician if you have had heart
disease, diabetes, glaucoma, a stroke, or high blood pressure. It stimulates the
heart muscle, and the result is increased blood pressure.
Do not give goldenseal to children under two. Start with small doses for older
children and adults
High doses may interfere with vitamin B metabolism.
Golden Seal should not be used by individuals with hypoglycemia.
main alkaloid constituent of Goldenseal is berberine. The topical application of
Goldenseal or berberine to the skin or eyes raises the possibility that an
adverse phototoxic reaction may result from an interaction between the alkaloid
These findings suggest that exposure to sunlight or artificial
light sources emitting UVA should be avoided when topical preparations derived
from Goldenseal or containing berberine are used.