Grape seed extract may cause excessive bleeding in those taking blood thinners.

Do not take if you are allergic to grapes.

May cause dizziness or nausea.

May interfere with cholesterol lowering drugs.
- J Med 2000;31(5-6):227-46 -- Effects of niacin-bound chromium and grape seed proanthocyanidin extract on the lipid profile of hypercholesterolemic subjects: a pilot study. -- Preuss HG, Wallerstedt D, Talpur N, Tutuncuoglu SO, Echard B, Myers A, Bui M, Bagchi D.

Can interact with other herbs changing the way they are absorbed.
 

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