The essential oil contains turpentines that are potentially allergenic. Report on 7 cases of patients with an allergic contact dermatitis due to tea tree oil. Two of them also exhibited from a delayed type IV hypersensitivity towards fragrance-mix or colophony suggesting the possibility of cross reaction or an allergic group reaction caused by contamination of the colophony with the volatile fraction of turpentines.
- Ann Dermatol Venereol 2001 Feb;128(2):123-6 -- Allergic contact dermatitis to cosmetics containing Melaleuca alternifolia (tea tree oil) -- Fritz TM, Burg G, Krasovec M.

Combined contact allergy to tea tree oil and lavender oil complicating chronic vulvovaginitis.
- Combined contact allergy to tea tree oil and lavender oil complicating chronic vulvovaginitis. -- Varma S, et al. -- Contact Dermatitis. 2000 May;42(5):309-10.

Allergic contact dermatitis due to tea tree oil was diagnosed. Tea tree oils are essential oils distilled from the leaves of myrtaceous trees and shrubs occurring in Australia and South-East Asia. 

The tea tree oil available in the Netherlands is distilled from the Melaleuca alternifolia and mainly contains eucalyptol. Eucalyptol is probably the most important allergen.
- Ned Tijdschr Geneeskd 1994 Apr 16;138(16):823-5 -- Allergic contact eczema due to 'tea tree' oil -- van der Valk PG, de Groot AC, Bruynzeel DP, Coenraads PJ, Weijland JW.

Tea tree oil may substitute Candida itching with allergy itching.
- Warning against a fashionable cure for vulvovaginitis. -- Wolner-Hanssen P, et al. Lakartidningen. -- 1998 Jul 22;95(30-31):3309-10.

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